Horizontal gene transfer of antibacterial genes

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Horizontal transfer beyond genes.

Horizontal gene transfer (HGT) is a major process in the evolution of bacteria and archaea (1–3) that is thought to be the principal source of functional innovation in microbial evolution (4, 5). The signal of vertical, tree-like evolution is detectable primarily among genes encoding components of information processing systems, whereas evolution of the operational genes (primarily, metabolic e...

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Horizontal gene transfer (HGT) is the movement of genetic information between organisms, a process that includes the spread of antibiotic resistance genes among bacteria (except for those from parent to offspring), fueling pathogen evolution. Many resistance genes evolved long ago in natural environments with no anthropogenic influence but these genes are now rapidly spreading to and among huma...

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ژورنال

عنوان ژورنال: Nature Reviews Genetics

سال: 2014

ISSN: 1471-0056,1471-0064

DOI: 10.1038/nrg3880